Insulin

Brand name

Rapid-acting analogue (clear)

  • Humalog® (insulin lispro)
  • NovoRapid® (insulin aspart)

Fast-acting (clear)

  • Humulin®-R
  • Novolin®ge Toronto

Intermediate-acting (cloudy)Humulin®-N

  • Humulin®-L
  • Novolin®ge NPH

Long-acting (cloudy)

  • Humulin®-U

Extended long-acting analogue

  • Lantus®* (insulin glargine)
  • Onset: 90 min
  • Duration: 24 h

Premixed (cloudy)Humalog® Mix25TM

  • Humulin® (20/80, 30/70)
  • Novolin®ge (10/90, 20/80, 30/70, 40/60, 50/50)
  • NovoMix® 30

Drug Class

  • Antidiabetic

Preparations

Rapid-acting analogue (clear)

  • Trade name:
    • Humalog® (insulin lispro)
    • NovoRapid® (insulin aspart)
  • Onset: 10–15 min
  • Peak: 60–90 min
  • Duration: 4–5 h

Fast-acting (clear)

  • Trade name:
    • Humulin®-R
    • Novolin®ge Toronto
  • Onset: 0.5–1 h
  • Peak: 2–4 h
  • Duration: 5–8 h

Intermediate-acting (cloudy)

  • Trade name:
    • Humulin®-N
    • Humulin®-L
    • Novolin®ge NPH
  • Onset: 1–3 h
    Peak: 5–8 h
    Duration: up to 18 h

Long-acting (cloudy)

  • Trade name:
    • Humulin®-U
  • Onset: 3–4 h
  • Peak: 8–15 h
  • Duration: 22–26 h

Extended long-acting analogue

  • Trade name:
    • Lantus®* (insulin glargine)
    • Onset: 90 min
    • Duration: 24 h

Premixed (cloudy)

  • Content: A single vial contains a fixed ratio of insulin (% rapid- or fast-acting to % intermediate-acting insulin)
  • Trade name:
    • Humalog® Mix25TM
    • Humulin® (20/80, 30/70)
    • Novolin®ge (10/90, 20/80, 30/70, 40/60, 50/50)
    • NovoMix® 30

Indications

  • Diabetes Melitus

Section

This document is prepared by the “Mental Health for All” team. This document is provided for information purposes only and does not necessarily represent endorsement by or an official position of the Essentials of Medicine. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient’s medical history.

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