- Synthetic cannabinoid
- Capsule: 1 mg
- Appetite inducer in HIV patients
- Pain killer
- Can be administered 1 to 2 mg up to three times daily
Amphetamines, cocaine, other sympathomimetic agents
- Additive hypertension,
- Possibly cardiotoxicity
Atropine, scopolamine, antihistamines, other anticholinergic agents
- Additive or super-additive tachycardia,
Amitriptyline, amoxapine, desipramine, other TCAs
- Additive tachycardia
Barbiturates, benzodiazepines, ethanol, lithium, opioids, buspirone, antihistamines, muscle relaxants, other CNS depressants
- CNS depression
- Decreased clearance of these agents, presumably via competitive inhibition of metabolism
- Increased theophylline metabolism reported with smoking of marijuana;
- effect similar to that following smoking tobacco
- Cross-tolerance and mutual potentiation
- Oral THC effects were enhanced by opioid receptor blockade.
- Increase in the positive subjective mood effects of smoked marijuana
Blood and Hematopoietic
Eye and Ear
- Visual disturbances
- Dry mouth
- CNS depression
- CNS stimulation,
- Circumoral paresthesia
- Emotional lability
Miscellaneous and Ill:
- Abnormal thinking
- Chest pain
- Lack of effect
- Face edema
- The effects of Cesamet may persist for a variable and unpredictable period of time following its oral administration. Adverse psychiatric reactions can persist for 48 to 72 hours following cessation of treatment.
- Cesamet has the potential to affect the CNS, which might manifest itself in dizziness, drowsiness, euphoria “high”, ataxia, anxiety, disorientation, depression, hallucinations and psychosis.
- Cesamet can cause tachycardia and orthostatic hypotension.
- Because of individual variation in response and tolerance to the effects of Cesamet, patients should remain under supervision of a responsible adult especially during initial use of Cesamet and during dose adjustments.
- Patients receiving treatment with Cesamet should be specifically warned not to drive, operate machinery, or engage in any hazardous activity while receiving Cesamet.